Chemical tongues: biomimetic recognition using arrays of synthetic polymers

Humans can taste and identify numerous comestibles by combining a small variety of receptor cells that exhibit broad-spectrum sensitivity with information processing based on pattern recognition. Recently, we have developed biosensing strategy called the “chemical tongue”, which mimics system employing polymeric materials containing various chemical structures labeled environment-responsive fluorophores in conjunction statistical techniques such as multivariate analysis machine learning. In this review, author outlines design polymer-based tongues using polyamino acids, DNAs, polyion complexes their applications complex biological samples, including cell suspensions, secretions, therapeutic antibodies. The chemical-tongue is capable recognizing samples unique manner does not, contrast to conventional approaches, rely specific interactions, thereby potentially opening avenues for unexplored uses polymers wide range research areas. This focus review describes human fluorogenic techniques. samples.